Novel Coronavirus – China

[Gray-Wolf]

Now I see why folk accuse me of 'talking Carp' in this thread!!!!

[Gray-Wolf]

So all of our cases , here in the UK,  'Recovered ' eh?

Out among us eh?

Chinese medical expert warns recovered coronavirus patients may still be contagious

WWW.SCMP.COM

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Head of frontline team fighting Covid-19 says some patients have been found to still carry the virus after getting better Scientists believe there is a low risk of...

 

[Gray-Wolf]

Yeah, all levelling off in Wuhan.....

China's Wuhan to build 19 more makeshift hospitals

WWW.GLOBALTIMES.CN

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Wuhan, the epicenter of the novel coronavirus outbreak, plans to build another 19 makeshift hospitals to receive more infected patients, local authorities...

 

[Gray-Wolf]

In case you didn't pick up on the significance of the Woman proving positive in Lebanon, how many refugee camps are there in Lebanon?

[swebby]

9 minutes ago, Snipper said:

If certain medical problems tend to run through families I don’t see why a proneness to one thing or another shouldn’t run with different races. It’s not racial just a matter of fact. 
 

My father died from prostate cancer, my brother died from prostate cancer.  I have had prostate cancer. 

You can have genetic variances (mutations if you wish) that can cause certain ailments. This should not however be confused with how viruses infect a human host.  A virus is asking one question, what species are you? Human? Dog? Zebra? Frog? It is not asking if you are Chinese, Bulgarian or Canadian.

Viruses look for a specific amino acid sequence within a protein that is located in a specific area (often cell walls), that they then commandeer to then gain access to the genetic reproduction machinery of the cell.  That amino acid sequence is likely to be present in 99.999% of the members of the species it is infecting.

It is possible for genetic variances to be contained within certain family groups, or even ethnic groups ,meaning that this group may produce a specific protein differently from your average person (sickle cell as an example of the latter).  It does not mean however that every person in that family/ethnic group is susceptible, it will only be those with the genetic variance. A virus that happens to be only effective on those with a specific genetic variance, is not going to be very successful. Basically, it will have evolved itself up a cul de sac.

 

 

[Gray-Wolf]

Some catch up on the 1918 Pandemic;

 

[Snipper]

4 minutes ago, swebby said:

You can have genetic variances (mutations if you wish) that can cause certain ailments. This should not however be confused with how viruses infect a human host.  A virus is asking one question, what species are you? Human? Dog? Zebra? Frog? It is not asking if you are Chinese, Bulgarian or Canadian.

Viruses look for a specific amino acid sequence within a protein that is located in a specific area (often cell walls), that they then commandeer to then gain access to the genetic reproduction machinery of the cell.  That amino acid sequence is likely to be present in 99.999% of the members of the species it is infecting.

It is possible for genetic variances to be contained within certain family groups, or even ethnic groups ,meaning that this group may produce a specific protein differently from your average person (sickle cell as an example of the latter).  It does not mean however that every person in that family/ethnic group is susceptible, it will only be those with the genetic variance. A virus that happens to be only effective on those with a specific genetic variance, is not going to be very successful. Basically, it will have evolved itself up a cul de sac.

 

 

I did mention prone to, which does not mean everyone. Who says that each virus must be successful? 

[swebby]

10 minutes ago, Snipper said:

I did mention prone to, which does not mean everyone. Who says that each virus must be successful? 

No reason why a virus must be successful, it is just a roll of the dice.

I do accept you have used the word prone, but you appear to have fallen foul of the common misconception (which is age old) that how the human body works will be different from one ethnic group and another. Biologically, humans are all the same and that is the level viruses (as well as bacterial, fungal, parasitical pathogens) operate on. The superficial stuff - skin, eye, hair colour is just that, superficial.

Edited February 21, 2020 by swebby

[Methuselah]

25 minutes ago, swebby said:

You can have genetic variances (mutations if you wish) that can cause certain ailments. This should not however be confused with how viruses infect a human host.  A virus is asking one question, what species are you? Human? Dog? Zebra? Frog? It is not asking if you are Chinese, Bulgarian or Canadian.

Viruses look for a specific amino acid sequence within a protein that is located in a specific area (often cell walls), that they then commandeer to then gain access to the genetic reproduction machinery of the cell.  That amino acid sequence is likely to be present in 99.999% of the members of the species it is infecting.

It is possible for genetic variances to be contained within certain family groups, or even ethnic groups ,meaning that this group may produce a specific protein differently from your average person (sickle cell as an example of the latter).  It does not mean however that every person in that family/ethnic group is susceptible, it will only be those with the genetic variance. A virus that happens to be only effective on those with a specific genetic variance, is not going to be very successful. Basically, it will have evolved itself up a cul de sac.

But, more specifically, it's also asking: do this person's (or cat's, dog's or houselfy's) cellular membranes incorporate the precise proteins that'll enable me to get inside...?

And, not everyone's will...

Edited February 21, 2020 by General Cluster

[Gray-Wolf]

2 minutes ago, General Cluster said:

But, more specifically, it's also asking: do this person's (or cat's, dog's or houselfy's) cellular membranes incorporate the precise proteins that'll enable me to get inside...?

And, not everyone's will...

On top of that each and every new 'Host' is a chance for the blighter to 'evolve' via natural mutations or recombinations.

As the 1918 Pandemic showed us a reasonably 'benign' infection can suddenly become 20 times as deadly over a matter of a few months?

The more folk providing a place to mutate the more likely a mutation occurring.

This is why it was essential to stop this coronavirus asap but ,sadly ,this did not happen and it swiftly gained the H2H potential?

We may even see it 'adapt' to ethnic differences to help it with its 'continuance'......we might think it is the asian population that is suffering worst with death rates there far higher than we see in europe but let it loose here and it may well adapt to better provide that service for europeans?

[Bristawl Si]

56 minutes ago, swebby said:

No reason why a virus must be successful, it is just a roll of the dice.

I do accept you have used the word prone, but you appear to have fallen foul of the common misconception (which is age old) that how the human body works will be different from one ethnic group and another. Biologically, humans are all the same and that is the level viruses (as well as bacterial, fungal, parasitical pathogens) operate on. The superficial stuff - skin, eye, hair colour is just that, superficial.

So, how do you explain, as following two examples show, the higher incidence amongst Afro-Caribbean heritage, of prostate cancer and sickle cell anaemia?

[Snipper]

50 minutes ago, swebby said:

No reason why a virus must be successful, it is just a roll of the dice.

I do accept you have used the word prone, but you appear to have fallen foul of the common misconception (which is age old) that how the human body works will be different from one ethnic group and another. Biologically, humans are all the same and that is the level viruses (as well as bacterial, fungal, parasitical pathogens) operate on. The superficial stuff - skin, eye, hair colour is just that, superficial.

Sorry have not fallen foul of the common misconception.

Agreed all humans are basically the same but because no place is the same there are differences caused by the living conditions and life style where they have evolved.
 

For example people living at the height of the Andes can cope with the rarified atmosphere. Transpose a lowland person there and they would find it very difficult to cope. So the two are not the same. 

[Gray-Wolf]

9 minutes ago, Snipper said:

Sorry have not fallen foul of the common misconception.

Agreed all humans are basically the same but because no place is the same there are differences caused by the living conditions and life style where they have evolved.
 

For example people living at the height of the Andes can cope with the rarified atmosphere. Transpose a lowland person there and they would find it very difficult to cope. So the two are not the same. 

Adapt and survive!

[Gael_Force]

News / COVID-19 | Faculty of Medicine | Imperial College London

WWW.IMPERIAL.AC.UK

@Gray-Wolf

66% undetected cases roaming the world kind of plays to your musings up thread.

[Methuselah]

10 minutes ago, Bristle boy said:

So, how do you explain, as following two examples show, the higher incidence amongst Afro-Caribbean heritage, of prostate cancer and sickle cell anaemia?

Sickle-shaped erythrocytes render folk more resistant to malarial infection; PC is likely a response to something in the Western diet...or environment.

Whatever the precise details, evolution by natural selection is almost always involved, somehow...?

[Gael_Force]

2 minutes ago, General Cluster said:

Sickle-shaped erythrocytes render folk more resistant to malarial infection; PC is likely a response to something in the Western diet...or environment.

Whatever the precise details, evolution by natural selection is almost always involved, somehow...?

Is there not a genetic marker for some female cancers (eg breast or cervical) hence they test and can offer more frequent screening. Why not similar with the male organs related to reproduction?

[Gray-Wolf]

9 minutes ago, General Cluster said:

Sickle-shaped erythrocytes render folk more resistant to malarial infection; PC is likely a response to something in the Western diet...or environment.

Whatever the precise details, evolution by natural selection is almost always involved, somehow...?

Look at our lovely Red Squirrels?

The Greys already had immunity to the lurgy they infected our guys with but, now, the few of our Reds that had the necessary immunity are staging a comeback?

As you say Pete, novel forcings lead to a natural selection favouring the survival mechanisms needed to 'cope' with those forcings?

But then some folk are colour blinded and so fail to see anything beyond?

Edited February 21, 2020 by Gray-Wolf

[Gray-Wolf]

Coronavirus clusters at Beijing hospitals ignite new fears

ASIA.NIKKEI.COM

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Spread of COVID-19 to capital comes as millions head back to work

 

[Bristawl Si]

So, basically you two are guessing, in response to my post.

Health authorities, and real medical experts all over the globe, say the two medical conditions i referred to are more prevalent in afro-caribbean and African people.

[Bristawl Si]

7 minutes ago, Gray-Wolf said:

Look at our lovely Red Squirrels?

The Greys already had immunity to the lurgy they infected our guys with but, now, the few of our Reds that had the necessary immunity are staging a comeback?

As you say Pete, novel forcings lead to a natural selection favouring the survival mechanisms needed to 'cope' with those forcings?

But then some folk are colour blinded and so fail to see anything beyond?

Nowt to do with "colour blinded", you plonk. Medical fact.

[Methuselah]

2 minutes ago, Bristle boy said:

So, basically you two are guessing, in response to my post.

Health authorities, and real medical experts all over the globe, say the two medical conditions i referred to are more prevalent in afro-caribbean and African people.

You might consider Googling 'Malaria, Sickle-Cell Trait', BB? Just sayin'!

[Gray-Wolf]

WHO concern at coronavirus cases outside China

WWW.BBC.CO.UK

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The comments come as Iran confirms two more deaths and says the virus may have spread to "all cities".

 

[Bristawl Si]

10 minutes ago, General Cluster said:

You might consider Googling 'Malaria, Sickle-Cell Trait', BB? Just sayin'!

So, how come sickle cell is highly prevalent amongst our own population of those with afro- carib or african heritage, BUT.....

Were born in UK and hardly ever, if ever, visit malaria risk countries?

[swebby]

39 minutes ago, Bristle boy said:

So, how do you explain, as following two examples show, the higher incidence amongst Afro-Caribbean heritage, of prostate cancer and sickle cell anaemia?

You are talking about hereditary disease.  The genetic variances that can occur in a family group, often with undesirable impacts on health. Basically when the body's biology goes wrong as a result of incorrect instructions.  

Whereas, I am talking about about how an infectious agent (a virus) attacks a host by using the correctly functioning biology that we all have.

You can obviously have a virus that is only active on those that are presenting a hereditary disease, but that virus is then only going to reproduce in a very small percentage of the population and will likely die out as a result.

[Gael_Force]

2 minutes ago, Bristle boy said:

So, how come sickle cell is highly prevalent amongst our own population of those with afro- carib or african heritage, BUT.....

Were born in UK and hardly ever, if ever, visit malaria risk countries?

This might sound stupid but how long did it take for white people to lose the skin pigmentation early humans would have brought out of Africa. I assume evolution is a slow process in genetic modification to other environmental factors.